Do enlarged lateral lymph nodes after CRT lead to preventable lateral local recurrences
Recent literature suggests that patients with enlarged lateral lymph nodes (>5mm on MRI), who had neoadjuvant chemoradiotherapy and standard TME, have an up to 80% local recurrence rate in the lateral compartment; half of which has no distant spread.
Currently, a multi-center pooled analysis is ongoing to study the (lateral) local recurrence rate in patients with low locally advanced rectal cancer with enlarged and/or heterogeneous lateral lymph nodes on the pre-treatment MRI.
Because of the low incidence of these specific patients, we need as many centers as possible to participate. Please contact us and join!
Miranda Kusters, surgeon, KWF Fellow.